Stem Cell Review: Stem Cells at a Glance (EP1)
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Stem Cells at a Glance
What are the differences between embryonic, adult and induced pluripotent stem cells? Where do the experts expect the next medical application will be for stem cells? Do stem cells promote regeneration? How are cell types interacting? How can induced pluripotent stem (iPS) cells revolutionize drug discovery? Can cell therapies be made into a viable business? How close are we to finding the right business model? Are investors interested in stem cells today? What is the political and ethical landscape like now that the Obama administration has taken over the White House?
This is the Episode 1 of the Stem Cell Review, aired on October 1st, 2009
Reviews
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Jecca
Created 4 months ago
Leonide Saad
Created 4 months ago
Excellent! Can't wait to watch the future episodes
Please bring in the most advanced companies!
Joanne Manaster
Created 4 months ago
A great place to begin
Thank you for this high quality production with lovely images and experts expressing their own thoughts and opinions. I will share this widely with my students here at the University of Illinois. My engineering students will especially appreciate the industry side of the field. I will also disseminate these through my other public outreach venues. I'm glad to see I can embed it, and will do so at www.joannelovesscience.com and my course websites. Kindly, Joanne
Created 4 months ago
KUDOS on Stem Cell Review...
Really well done...
This will be a great 'Primer' for all of us on the business side of Biotech.
congrats to the team.
Marc Lemonnier
Created 4 months ago
Very impressive. A trully innovative tool for the biopharma community.
Looking forward to watching the next episodes of this series, AND hopefully future series focused on other therapeutic areas of interest (antibacterials!). Congratulations to the team.
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<all>Researchers are using stem cells as tools for disease study, drug screening, clinical trial strategy, and personalized medicine. The induced Pluripotent Stem cell (iPS) is giving us a chance to rethink the way we are developing new drugs. These iPS cells are usually created from somatic cells (such as skin), and not embryos or adult stem cells. In creating iPS from patients' diseased cells, scientists can study the disease in vitro, looking for disease phenotypes, applying microenvironmental stress, and testing new drugs. Compared to animal model testing (e.g. mice), this represents a significant breakthrough, that can be used to validate clinical development strategy and test efficacy in specific groups of patients. iPS is bringing a revolution in drug discovery methodology which is being used to bridge genetics, cell biology, and physiology.
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Credits
In Order of Appearance:
GUESTS
George Q. Daley, M.D., Ph.D. - Harvard Medical School Samuel E. Lux, IV Chair in Hematology, Director, Stem Cell Transplantation Program, Children's Hospital Boston
Dan Marshak Ph.D. - PerkinElmer, Inc. Chief Scientific Officer and President, Greater China
Alan Colman, Ph.D., M.A. - A*STAR Institute of Medical Biology Executive Director, Singapore Stem Cell Consortium (SSCC); Principal Investigator, Institute of Medical Biology
John Sinden, Ph.D. - ReNeuron Group Chief Scientific Officer
Dr. Ronald D.G. McKay - NIH Senior Investigator, Laboratory of Molecular Biology, Porter Neuroscience Research Center, NINDS (National Institute of Neurological Disorders and Stroke) - a part of the NIH (National Institutes of Health)
Shinya Yamanaka, M.D., Ph.D. - UCSF and Kyoto University Senior Investigator, Gladstone Institute of Cardiovascular Disease, L.K. Whittier Foundation Investigator in Stem Cell Biology; Professor of Anatomy, University of California, San Francisco; Director, Center for iPS Cell Research and Application (CiRA), Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University; Professor, Department of Stem Cell Sciences, Institute for Frontier Medical Sciences
Gregory A. Bonfiglio - Proteus Venture Partners Managing Partner
Alan O. Trounson, Ph.D. - California Institute for Regenerative Medicine President
IMAGES
Stem Cell Review Studio Background Pictures provided by the California Institute of Regenerative Medicine
- Jecca: Eyes from "Synapse"
- Unknown: Skin Stimulation
- ReNeuron: XY point 1 (well A1)
- ReNeuron: CTX0E03 2wk diff nestin green Hoechst blue
- ReNeuron: CTX0E03 4d diff purmorph b3 green DCX red hoechst blue
- Sven Hoppe: Human cells in a 37°C incubator
- CIRM: Human Embryonic Stem Cells
- CIRM: motor neuron progenitors
- CIRM: neurosphere giving rise to progenitors
- Unknown: Female doctor giving an injection to a patient, selective focus, canon 1Ds mark III
- CIRM: Neural stem cells in the brain
- CIRM: Heart muscle precursor cells
- Sergey Ivanov: Horse clearing off a hurdle at show jumping competition.
- AP Photo / Ron Edmonds: President Barack Obama signs executive order on stem cells
- Unknown: Obama and Stem Cells
- Time Magazine Cover: How the Coming Revolution in Stem Cells could save your life (KIT RODOLFA/HARVARD STEM CELL INSTITUTE. INSETS, FROM LEFT: - - CALLIE SHELL/AURORA FOR TIME; ISHIKA MOHAN/FOX SEARCHLIGHT)
A Special Thanks to:
- Ferghana Partners Group
- ISSCR / The International Society for Stem Cell Research
- Genetics Policy Institute / World Stem Cell Summit
- Hilton Hotels / The Hilton Diagonal Mar in Barcelona
MUSIC
Protest by soundroll Five Tribes by ventilo35
Last but not Least!
- Freya Alugas
- Pat Becker
- Melissa Carpenter
- Ellen Charles
- Meagan Comerford
- Karena Essex
- Elisabet Fabregas
- Mario Fante
- Rocio Fontela
- Liz Freyn
- Don Gibbons
- Raj Kaur
- Paul Laland
- Gemma Llamas
- Jillian McFady
- Mary Lou McKeone
- Didier Montarras
- Mario Oliete
- Jose Maria Ruiz
- Valerie Tucker
- Kristen April Uekermann
- Nancy Witty
- Jessica Yingling
About
Acknowledgements
Hi quality, highly informative, excellent content and delivery of messages through sophisticated, clear audio-visual design. The very top quality people in the field delivering intelligent nuggets of important information with honesty and candor. This is the program to watch and watch for more!